Aptamers: Chemistry Bests Mother Nature’s Antibodies

• Discovered ~20 years ago, aptamer applications are booming • Modified oligos and nucleotide triphosphates play pivotal roles • World’s first chemical guided missile could be the answer to wiping out cancer • Are antibodies passé? Aptamers are nucleic acids … Continue reading

Advances in Nucleic Acid-Based Therapeutics Against Alzheimer’s

Dementia Develops in Someone in the World Every 3 Seconds Nucleic Acid-Based Approaches for an Alzheimer’s Drug Are Advancing Ionis Pharmaceuticals is First to Begin Clinical Trials with Antisense Oligonucleotide Targeting Tau The concept of nucleic acid-based therapeutics, as originally … Continue reading

Jerry’s Favs from the Recent 7th Cambridge Symposium

DNA Can Function as an Enzyme RNA Polymerase Activity Without Proteins Systemic Brain Delivery of Therapeutic Oligos The 7th Cambridge Symposium on Nucleic Acids Chemistry and Biology took place September 3-6, 2017 at historic Queens’ College, Cambridge, which was founded … Continue reading

Advances in Aptamer Applications – Part 2

Top Cited Aptamer Publications Over the Past Three Years Jerry’s Picks for Top 3 Aptamer Publications So Far This Year TriLink Products Cited in Numerous Aptamer Publications Aptamers are highly structured nucleic acids that bind to a specific target molecule. RNA … Continue reading